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Immunomodulators

These sections summarize the data on IL-6 inhibitors, kinase inhibitors, and other immunomodulators.

Immunomodulators Summary Recommendations

Review the Panel’s recommendations on the use of immunomodulators in patients with COVID-19.

Colchicine

Colchicine is an anti-inflammatory drug that is being evaluated to treat COVID-19.

Corticosteroids

Corticosteroids are anti-inflammatory drugs that may benefit particular patients with COVID-19.

Fluvoxamine

Fluvoxamine is an SSRI used to treat mood disorders that is being evaluated to treat COVID-19.

GM-CSF Inhibitors

Review the data on the use of GM-CSF inhibitors for the treatment of COVID-19.

IVIG - Non-SARS-CoV-2

Review the data on the use of non-SARS-CoV-2 specific IVIG in patients with COVID-19.

Interferons

Interferons are a group of antiviral cytokines that are being evaluated to treat COVID-19.

Interleukin-1 Inhibitors

IL-1 inhibitors are a group of anti-inflammatory drugs that are being evaluated to treat COVID-19.

Interleukin-6 Inhibitors

IL-6 inhibitors are a group of anti-inflammatory drugs that are being evaluated to treat COVID-19.

Kinase Inhibitors

JAK and BTK inhibitors are immunomodulatory drugs that are being evaluated to treat COVID-19.

Table: Characteristics of Immunomodulators

This table summarizes key characteristics of immunomodulators that have been evaluated for COVID-19.