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Antiviral Therapy

These sections summarize the data on remdesivir, chloroquine, and other antiviral medications.

Antiviral Therapy Summary Recommendations

Review the Panel’s recommendations on the use of antiviral therapies in patients with COVID-19.


Remdesivir is a nucleotide analogue prodrug that is approved to treat COVID-19 in certain patients.

Ritonavir-Boosted Nirmatrelvir (Paxlovid)

Read about using ritonavir-boosted nirmatrelvir in patients with COVID-19.


Read about using molnupiravir in patients with COVID-19.

Chloroquine or Hydroxychloroquine and/or Azithromycin

Chloroquine and hydroxychloroquine are antimalarial drugs that were studied to treat COVID-19.


Interferons are a group of antiviral cytokines that are being evaluated to treat COVID-19.


Ivermectin is an antiparasitic drug that is being evaluated to treat COVID-19.

Lopinavir/Ritonavir and Other HIV Protease Inhibitors

Protease inhibitors are antiretroviral drugs for HIV that were studied as treatments for COVID-19.


Nitazoxanide is an antiparasitic drug that is being evaluated to treat COVID-19.

Table: Characteristics of Antiviral Agents

This table summarizes key characteristics of antiviral agents that have been evaluated for COVID-19.